Landmark Papers on Blood and Component Transfusion Therapy in the Critically Ill: A Critical Analysis

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CARING FOR THE CRITICALLY ILL PATIENT Anemia and Blood Transfusion in Critically Ill Patients

ANEMIA IS A COMMON PROBLEM in critically ill patients admitted to intensive care units (ICUs). Deleterious effects of anemia include increased risk of cardiacrelated morbidity and mortality, as well as a generalized decrease in oxygencarrying capacity. Consequences of anemia may be compounded in this population since critical illness often increases metabolic demands. Among the many causes of a...

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Red blood cell transfusion in the critically ill patient

Anaemia is a common finding in critically ill patients. There are often multiple causes. Obvious causes include surgical bleeding and gastrointestinal haemorrhage but many patients have no overt bleeding episodes. Phlebotomy can be a significant source of blood loss. In addition, critically ill patients have impaired erythropoiesis as a consequence of blunted erythropoietin production and direc...

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Blood transfusion in the critically ill: does storage age matter?

Morphologic and biochemical changes occur during red cell storage prior to product expiry, and these changes may hinder erythrocyte viability and function following transfusion. Despite a relatively large body of literature detailing the metabolic and structural deterioration that occurs during red cell storage, evidence for a significant detrimental clinical effect related to the transfusion o...

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Transfusion practice and blood stream infections in critically ill patients.

STUDY OBJECTIVE To examine the relationship between packed RBC (pRBC) transfusion and the development of ICU-acquired bloodstream infections (BSIs) DESIGN Secondary analysis of a large, prospective, observational study of transfusion practice in critically ill patients. SETTING A total of 284 adult ICUs in the United States. PATIENTS Critically ill adults who lacked BSIs both at ICU admis...

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ژورنال

عنوان ژورنال: Indian Journal of Critical Care Medicine

سال: 2019

ISSN: 0972-5229,1998-359X

DOI: 10.5005/jp-journals-10071-23254